Name: TPM1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： TPM1抗原（重組蛋白）

英文名稱： TPM1 Antigen (Recombinant Protein)

別名： CMH3; TMSA; CMD1Y; C15orf13; HTM-alpha

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	Tropomyosin 1 (alpha)
Synonyms:	CMH3; TMSA; CMD1Y; C15orf13; HTM-alpha
Swissprot:	P09493
Gene Accession:	BC007433
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

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