購物車
幫助
021-54845833/15800441009
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述
|
Full name: |
neurofilament, light polypeptide |
|
Synonyms: |
NFL, NF-L, NF68, CMT1F, CMT2E |
|
Swissprot: |
P07196 |
|
Gene Accession: |
BC066952 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
