購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：MPZL1抗原（重組蛋白）
英文名稱(chēng) MPZL1 Antigen (Recombinant Protein)
別 名： PZR; PZRa; PZRb; PZR1b; MPZL1b
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類(lèi)別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 70-269 amino acids of human MPZL1 |
|
Full name: |
myelin protein zero like 1 |
|
Synonyms: |
PZR; PZRa; PZRb; PZR1b; MPZL1b |
|
Swissprot: |
O95297 |
|
Gene Accession: |
BC007881 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. |
