購物車
幫助
021-54845833/15800441009
中文名稱： IMPDH2 抗原（重組蛋白）
英文名稱： IMPDH2 Antigen (Recombinant Protein)
儲(chǔ) 存： 冷凍（-20℃）
別 名： IMP (inosine 5'-monophosphate) dehydrogenase 2; IMPD2; IMPDH-II
相關(guān)類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 114-237 amino acids of human IMPDH2 |
技術(shù)規(guī)格
|
Full name: |
IMP (inosine 5'-monophosphate) dehydrogenase 2 |
|
Synonyms: |
IMPD2; IMPDH-II |
|
Swissprot: |
P12268 |
|
Gene Accession: |
BC006124 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
