購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：小鼠抗MSL2單克隆抗體
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Background: |
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. |
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Applications: |
WB |
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Name of antibody: |
MSL2 |
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Immunogen: |
Fusion protein of human MSL2 |
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Full name: |
MSL complex subunit 2 |
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Synonyms: |
MSL-2; MSL2L1; RNF184 |
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SwissProt: |
Q9HCI7 |
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WB Predicted band size: |
63 KD |
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WB Positive control: |
Hela cell lysate |
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WB Recommended dilution: |
500-2000 |
