購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱： 兔抗PFKFB4多克隆抗體
英文名稱： Anti-PFKFB4 rabbit polyclonal antibody
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PFKFB4
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is one of four bifunctional kinase/phosphatases that regulate the concentration of the glycolytic byproduct fructose-2,6-bisphosphate (F2,6BP). The encoded protein is highly expressed in cancer cells and is induced by hypoxia. This protein is essential to the survival of cancer cells under conditions of hypoxia, because it increases the amount of F2,6BP and ATP at a time when the cell cannot produce much of them. This finding suggests that this protein may be a good target for disruption in cancer cells, hopefully imperiling their survival. Several transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
PFKFB4 |
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Immunogen: |
Synthetic peptide of human PFKFB4 |
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Full name: |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
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SwissProt: |
Q16877 |
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ELISA Recommended dilution: |
2000-5000 |
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WB Predicted band size: |
54 kDa |
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WB Positive control: |
Human testis tissue lysate |
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WB Recommended dilution: |
200-1000 |
