久久综合九九-久久综合九九亚洲一区-久久综合九色-久久综合九色欧美综合狠狠-久久综合九色婷婷97-久久综合九色综合8888

歡迎來到上海通蔚!

021-54845833/15800441009

品質保證 · 通蔚試劑

當前位置: 首頁 > 科研產品 > 科研抗體 > 一抗 > 兔抗FOXO1/3/4(Phospho-Thr24/32) 多克隆抗體

產品中心

  • 兔抗FOXO1/3/4(Phospho-Thr24/32) 多克隆抗體

    規格:
    價格:
    • 品牌 : 通蔚生物
    • 目錄號 : TW21441
    • 應用 : 僅供科研使用
    • 貨期 : 現貨
    • 規格 :100ul/200ul/25ul
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關產品

中文名稱: 兔抗FOXO1/3/4(Phospho-Thr24/32) 多克隆抗體

英文名稱: Anti-FOXO1/3/4(Phospho-Thr24/32) rabbit polyclonal antibody

別      名: FKH1; FKHR; FOXO1A/FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2/AFX; AFX1; MLLT7

相關類別: 一抗

儲      存: 冷凍(-20℃) 避光

宿      主: Rabbit

抗      原: FOXO1/3/4(Phospho-Thr24/32)

反應種屬: Human Mouse

標  記 物: Unconjugate

克隆類型: rabbit polyclonal

技術規格

Background:

Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts syngernistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells.

Applications:

WB

Name of antibody:

FOXO1/3/4(Phospho-Thr24/32)

Immunogen:

Peptide sequence around phosphorylation site of threonine 24/32(S-C-T(p)-W-P) derived from Human FOXO1/3/4-pan .

Full name:

forkhead box O1/3/4

Synonyms:

FKH1; FKHR; FOXO1A/FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2/AFX; AFX1; MLLT7

SwissProt:

Q12778/O43524/P98177

WB Predicted band size:

70/71/54 kDa

WB Positive control:

293 cells lysates treated with serum

WB Recommended dilution:

500-1000


主站蜘蛛池模板: 中文字幕欧美日韩在线不卡 | 精品久久久久久蜜臂a∨ | 免费看真人a一级毛片 | 米奇精品一区二区三区 | 中文字幕亚洲综合久久男男 | 亚洲国内自拍愉拍20页 | 五月天婷婷免费观看视频在线 | 久久精品综合国产二区 | 99er久久| 中文国产成人精品少久久 | 久久精品日本免费线 | 亚洲成人一区二区 | 男女生性毛片免费观看 | 777午夜精品被窝影院 | 国内精品在线视频 | 在线500福利视频国产 | 免费爱爱 | 欧美中文字幕在线看 | 欧美男女视频 | 成人a毛片视频免费看 | 噜鲁射图片 | 香蕉色香蕉在线视频 | 玖玖国产精品视频 | 全部费免一级毛片不收费 | 日韩dv| 99久久综合狠狠综合久久一区 | www.四虎影| 男人猛桶女人下面视频国产 | 亚洲精品亚洲九十七页 | 久久久精品一区 | 日本免费特黄aa毛片 | 奇米色在线 | 日韩一区国产二区欧美三区 | 国产毛片在线 | 男女啪啪猛烈免费网站 | 免费一区二区 | 久久精品免视看国产盗摄 | 国产精品免费看 | baoyu777永久免费视频 | 欧美国产影院 | 米奇影视7777 |