久久综合九九-久久综合九九亚洲一区-久久综合九色-久久综合九色欧美综合狠狠-久久综合九色婷婷97-久久综合九色综合8888

歡迎來到上海通蔚!

021-54845833/15800441009

品質保證 · 通蔚試劑

當前位置: 首頁 > 科研產品 > 科研抗體 > 一抗 > 兔抗FOXO1/3/4(Phospho-Thr24/32) 多克隆抗體

產品中心

  • 兔抗FOXO1/3/4(Phospho-Thr24/32) 多克隆抗體

    規格:
    價格:
    • 品牌 : 通蔚生物
    • 目錄號 : TW21441
    • 應用 : 僅供科研使用
    • 貨期 : 現貨
    • 規格 :100ul/200ul/25ul
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關產品

中文名稱: 兔抗FOXO1/3/4(Phospho-Thr24/32) 多克隆抗體

英文名稱: Anti-FOXO1/3/4(Phospho-Thr24/32) rabbit polyclonal antibody

別      名: FKH1; FKHR; FOXO1A/FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2/AFX; AFX1; MLLT7

相關類別: 一抗

儲      存: 冷凍(-20℃) 避光

宿      主: Rabbit

抗      原: FOXO1/3/4(Phospho-Thr24/32)

反應種屬: Human Mouse

標  記 物: Unconjugate

克隆類型: rabbit polyclonal

技術規格

Background:

Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts syngernistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells.

Applications:

WB

Name of antibody:

FOXO1/3/4(Phospho-Thr24/32)

Immunogen:

Peptide sequence around phosphorylation site of threonine 24/32(S-C-T(p)-W-P) derived from Human FOXO1/3/4-pan .

Full name:

forkhead box O1/3/4

Synonyms:

FKH1; FKHR; FOXO1A/FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2/AFX; AFX1; MLLT7

SwissProt:

Q12778/O43524/P98177

WB Predicted band size:

70/71/54 kDa

WB Positive control:

293 cells lysates treated with serum

WB Recommended dilution:

500-1000


主站蜘蛛池模板: 狠狠操在线观看 | 亚洲国产激情一区二区三区 | 国产99re| 欧美日韩永久久一区二区三区 | 久久综合偷偷噜噜噜色 | 欧美激情视频一区 | 天天爽夜夜爽视频 | 国产99精品| 欧美午夜在线观看理论片 | 尤物在线视频 | 国产成人亚洲综合在线 | 国产91在线视频 | 国产在线视频凹凸分类 | 四虎b3t77com| 成人区在线观看免费视频 | 欧美色综合图区 | 999yy成年在线视频免费看 | 亚洲一区二区三区在线免费观看 | 久久久久视频精品网 | 成人黄色小视频 | 综合图区亚洲白拍在线 | 日韩国产精品欧美一区二区 | 久久精品精品 | 亚洲夂夂婷婷色拍ww47 | 亚洲精品久久成人福利 | 手机看片福利永久国产日韩 | 精品久久中文久久久 | 亚洲视频在线观看 | 湿湿影院在线观看 | 伊人操| 国内久久精品 | 国产香蕉精品视频 | 国产偷视频 | 亚洲欧美日韩一区成人 | 久久在线播放 | 99热在线观看精品 | 99麻豆久久久国产精品免费 | 国内久久精品 | 久久精品国内一区二区三区 | 成人欧美视频 | 国产羞羞事1000部在线观看 |