購(gòu)物車
幫助
021-54845833/15800441009
英文名稱： Anti-SELENOS rabbit polyclonal antibody
別 名： selenoprotein S; SELS; VIMP; ADO15; SBBI8; SEPS1;
相關(guān)類別 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主：Rabbit
抗 原： SELENOS
反應(yīng)種屬： Human, Mouse, Rat
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion. An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene (PMID:23614019). [provided by RefSeq, Jul 2017] |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
SELENOS |
|
Immunogen: |
Synthetic peptide of human SELENOS |
|
Full name: |
selenoprotein S |
|
Synonyms: |
SELS; VIMP; ADO15; SBBI8; SEPS1; AD-015 |
|
SwissProt: |
Q9BQE4 |
|
IHC positive control: |
Human brain and Human renal cancer |
|
IHC Recommend dilution: |
25-100 |
