購物車
幫助
021-54845833/15800441009
中文名稱：TNK2 抗原（重組蛋白）
英文名稱： TNK2 Antigen (Recombinant Protein)
別 名： tyrosine kinase, non-receptor, 2; ACK; ACK1; ACK-1; p21cdc42Hs
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human TNK2 |
|
Full name: |
tyrosine kinase, non-receptor, 2 |
|
Synonyms: |
ACK; ACK1; ACK-1; p21cdc42Hs |
|
Swissprot: |
Q07912 |
|
Gene Accession: |
BC028164 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. |
