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  • PSMC6 抗原(重組蛋白)

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    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17609
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :100ug
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中文名稱:  PSMC6 抗原(重組蛋白)

英文名稱: PSMC6 Antigen (Recombinant Protein)

別      名: proteasome 26S subunit, ATPase 6; P44; p42; SUG2; CADP44; HEL-S-73

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 190-389 amino acids of human PSMC6


技術(shù)規(guī)格

Full name:

proteasome 26S subunit, ATPase 6

Synonyms:

P44; p42; SUG2; CADP44; HEL-S-73

Swissprot:

P62333

Gene Accession:

BC005390

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.


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