購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
DCTN2 |
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Immunogen: |
Fusion protein of human DCTN2 |
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Full name: |
dynactin 2 (p50) |
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Synonyms： |
RBP50; DCTN50; HEL-S-77; DYNAMITIN |
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SwissProt: |
Q13561 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human liver cancer and human cervical cancer |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
44 kDa |
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WB Positive control: |
293T cells and mouse brain tissue |
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WB Recommended dilution: |
200-1000 |
