購物車
幫助
021-54845833/15800441009
中文名稱：DCT 抗原（重組蛋白）
英文名稱： DCT Antigen (Recombinant Protein)
別 名： dopachrome tautomerase; TRP-2; TYRP2
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 222-472 amino acids of human DCT |
|
Full name: |
dopachrome tautomerase |
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Synonyms: |
TRP-2; TYRP2 |
|
Swissprot: |
P40126 |
|
Gene Accession: |
BC028311 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The human TYRP2 protein has 83% identity and 90% similarity to the mouse sequence and has all the structural characteristics of the tyrosinase protein family, including a signal peptide, 15 conserved cysteine residues, 2 copper-binding domains, and a C-terminal membrane-spanning region. Northern blot analysis showed that TYRP2 is expressed at high levels in human melanoma cells. Its expression is regulated by the microphthalmia-associated transcription factor (MITF). |
