Name: CHIT1 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： CHIT1 抗原（重組蛋白）

英文名稱： CHIT1 Antigen (Recombinant Protein)

別名： chitinase 1; CHI3; CHIT; CHITD

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 267-466 amino acids of human CHIT1

技術(shù)規(guī)格

Full name:	chitinase 1
Synonyms:	CHI3; CHIT; CHITD
Swissprot:	Q13231
Gene Accession:	BC103695
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

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