久久综合九九-久久综合九九亚洲一区-久久综合九色-久久综合九色欧美综合狠狠-久久综合九色婷婷97-久久综合九色综合8888

歡迎來到上海通蔚!

021-54845833/15800441009

品質保證 · 通蔚試劑

當前位置: 首頁 > 科研產品 > 科研抗體 > 一抗 > 兔抗LAMB2多克隆抗體

產品中心

  • 兔抗LAMB2多克隆抗體

    規格:
    價格:
    • 品牌 : 通蔚生物
    • 目錄號 : TW11098
    • 應用 : 僅供科研使用
    • 貨期 : 現貨
    • 規格 :100ul/200ul/25ul
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關產品

中文名稱: 兔抗LAMB2多克隆抗體

英文名稱: Anti-LAMB2 rabbit polyclonal antibody

別     名: LAMS; NPHS5

抗     原: LAMB2

儲     存: 冷凍(-20℃) 避光

宿     主: Rabbit

反應種屬: Human Mouse Rat

相關類別: 一抗

標 記 物: Unconjugate

克隆類型: Unconjugate

技術規格

Background:

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form. The full-length nature of the spliced transcript is not known.

Applications:

WB

Name of antibody:

LAMB2

Immunogen:

Synthesized peptide derived from internal of human LAMB2.

Full name:

laminin, beta 2 (laminin S)

Synonyms:

LAMS; NPHS5

SwissProt:

P55268

WB Predicted band size:

196 kDa

WB Positive control:

RAW264.7 cells lysate

WB Recommended dilution:

500-3000





主站蜘蛛池模板: 黄色大全网站 | h片免费 | 国产热热| 欧美一区二区三区精品国产 | 欧美激情精品久久久久久久久久 | 日本一级看片免费播放 | 欧美日本在线 | 久久精品国产亚洲网站 | 日本a在线 | 99re视频精品全部免费 | 99视频在线观看免费 | 国产精品第六页 | 久久我们这里只有精品国产4 | 国产一区二区三区视频在线观看 | 午夜免费 | 91探花视频在线观看 | 手机看片国产福利 | 日韩专区亚洲精品欧美专区 | 成人a在线观看 | 婷婷成人基地 | 日韩视频在线观看一区 | 欧美天堂在线视频 | 亚洲综合无码一区二区 | 亚洲精品亚洲人成在线播放 | 九九九国产视频 | 久草在线视频在线观看 | 久久91av | 精品日韩一区二区 | 亚洲精品视频久久久 | 一级a俄罗斯毛片免费 | 亚洲第一综合网站 | 在线视频一区二区三区四区 | 日本亚洲一区二区 | 日韩免费片 | 日本一区二区三区免费高清在线 | 久久996re热这里有精品 | 国产成人精品免费视频 | 一区二区三区中文国产亚洲 | 日本精品久久久久中文字幕 1 | 伊人久久影院 | 中文字幕亚洲综合精品一区 |