中文名稱：DDB2抗原（重組蛋白）

英文名稱：DDB2 Antigen (Recombinant Protein)

儲存：冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 128-427 amino acids of human DDB2

技術規格

Full name:

damage-specific DNA binding protein 2

Synonyms:

XPE; DDBB; UV-DDB2

Swissprot:

Q92466

Gene Accession:

BC000093

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

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DDB2抗原（重組蛋白）說明書
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021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎培養基

完全培養基

原代細胞

細胞專用培養基

菌株

生化試劑

病理染色液

科研抗體

標準品

血清

形態病理檢測

分子病理

超微病理

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DDB2抗原（重組蛋白）

Full name:	damage-specific DNA binding protein 2
Synonyms:	XPE; DDBB; UV-DDB2
Swissprot:	Q92466
Gene Accession:	BC000093
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.